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Monday, May 18, 2020 | History

1 edition of Experimental otitis media in chinchillas found in the catalog.

Experimental otitis media in chinchillas

Experimental otitis media in chinchillas

  • 367 Want to read
  • 7 Currently reading

Published by Annals Pub. Co. in St. Louis Mo .
Written in English

    Subjects:
  • Otitis media,
  • Chinchillas,
  • Immune response

  • Edition Notes

    Includes bibliographical references

    Other titlesComparison of the middle ear immune responses to S pneumoniae types 3 and 23, Baseline immunological investigation
    SeriesThe annals of otology, rhinology & laryngology. Supplement -- 93, Annals of otology, rhinology & laryngology -- 93
    ContributionsWatanabe, Noritake, Watanabe, Noritake.
    The Physical Object
    Pagination16 p. :
    Number of Pages16
    ID Numbers
    Open LibraryOL22775400M

    The chinchillas tested had a bacterial infection caused by Haemophilus influenzae bacteria, a common cause of otitis media, according to Kohane. All 10 chinchillas who received the new gel were. @article{osti_, title = {Passage of albumin from the middle ear to the inner ear in otitis media in the chinchilla}, author = {Goldberg, B and Goycoolea, M V and Schleivert, P M and Shea, D and Schachern, P and Paparella, M M and Carpenter, A M}, abstractNote = {A study of the permeability of the middle ear-inner ear interface for macromolecules was carried out in chinchillas with open.

    In all areas of the world, upper respiratory tract (URT) infections and their complicating sequelae are the leading causes of acute infectious morbidity. Otitis media (OM), or inflammation of the middle ear, is one of these complicating sequelae of URT infections and is indeed a major health care concern of childhood. This chapter discusses OM’s etiologic agents, animal models, and. Methods Experimental otitis media was induced in chinchillas by transbullar injection of nontypable H. influenzae. Animals were killed in a time series and the surface of the middle‐ear mucosa was examined by scanning electron microscopy (SEM) for the presence of bacterial by:

    T1 - The determination of phospholipids in middle ear effusion from experimental otitis media in the Chinchilla. AU - Tsuruhara, Keizo. AU - Moreano, Alex. AU - Juhn, Steven S. AU - Kumazawa, Tadami. PY - /1/1. Y1 - /1/1Author: Keizo Tsuruhara, Alex Moreano, Steven K. Juhn, Tadami Kumazawa. Bacterial Biofilms in Otitis Media Article Literature Review in The Pediatric Infectious Disease Journal 26(10 Suppl):S November with 48 Reads How we measure 'reads'.


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Experimental otitis media in chinchillas Download PDF EPUB FB2

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.

Experimental Otitis Media in Chinchillas Following Nasal Colonization with Type 7F Streptococcus pneumoniae: Prevention after Vaccination with Pneumococcal Capsular Polysaccharide. The chinchilla is the traditional animal model for most types of research related to the ear, specifically, hearing loss and otitis media.

The chapter discusses all the different experimental models such as the models related to aural diseases, models related to hearing loss, and the models of aural pathologic conditions associated with hearing Price: $ Experimental otitis media in gerbils and chinchillas with Streptococcus pneumoniae, Haemophilus influenzae, and other aerobic and anaerobic by:   Chinchillas were colonized intranasally with type 7F Streptococcus pneumoniae, and pneumococcal otitis media developed in greater than 50% of the animals during the first week after negative middle ear pressure ( mm Hg) was briefly by: Acute otitis media was produced in chinchillas by inoculation of type 23 Strep- tococcus pneumoniae directly into the middle ear cavity by tympanotomy.

The gerbils were found to be useful as an alternative animal model for the study of otitis media of bacterial etiology. Experimental otitis media in gerbils and chinchillas with Streptococcus pneumoniae, Haemophilus influenzae, and other aerobic and anaerobic bacteria.

| Cited by:   Otitis media was induced in chinchillas by intrabullar injection of type 3 Streptococcus pneumoniae. It was found that the severity of a primary infection was related to the dose of bacteria injected, and animals that had recovered from a primary infection were resistant to reinfection with type 3 S by: Following complete anesthesia induc- OTITIS MEDIA: THE CHINCHILLA MODEL tion with ketamine hydrochloride, the technician grasps the chinchilla around the thorax and forelimbs with the left hand.

Holding the chinchilla with the left naris in the most dependent position, the technician inserts the blunt needle mm into the right naris and slowly instills the sterile saline solution into the nasal by: The natural history of experimental pneumococcal otitis media (POM) was studied in chinchillas following direct inoculation of Streptococcus pneumoniae into the middle ear cavity and following.

Giebink et al. demonstrated over 30 years ago that the chinchilla middle ear could be used as a model for pneumococcal otitis media. Since that time, Haemophilus influenzae and Moraxella catarrhalis have been shown to be capable of inducing bacterial otitis media in the chinchilla [5, 6].

The model bears many similarities to human disease and can be induced by intranasal Cited by: 8. Acute otitis media was produced in chinchillas by inoculation of type 23 Streptococcus pneumoniae directly into the middle ear cavity by tympanotomy.

During the first three days after inoculation, inflammatory cells were seen in the mucoperiosteum of the middle ear. Otitis media developed in 67% of chinchillas inoculated intranasally with type 7 Streptococcus pneumoniae and influenza A virus.

Only 4% of chinchillas inoculated with influenza alone and 21% of chinchillas inoculated with S. pneumoniae alone developed otitis by: Experimental otitis media in gerbils and chinchillas with Streptococcus pneumoniae, Haemophilus influenzae, and other aerobic and anaerobic bacteria.

By R. We hypothesized that the chinchilla model of otitis media may be an appropriate system with which to study the role of cytokines in otitis media with effusion. To begin to investigate this possibility, 30 chinchillas underwent surgical blockage of the eustachian tube (ET) to promote effusion by: Up-regulation of macrophage migration inhibitory factor induced by endotoxin in experimental otitis media with effusion in mice 8 July | Acta Oto-Laryngologica, Vol.No.

7 Middle ear sample collection in the chinchillaCited by: conclude that, although the pathologic process of acute pneumococcal otitis media otitis media Subject Category: Diseases, Disorders, and Symptoms see more details in the chinchilla chinchilla Subject Category: Organism Names see more details differs from pneumococcal otitis in humans in both the extension and severity of the middle ear infection, this model will allow comparison Cited by: Giebink GS, Payne EE, Mills EL, et al: Experimental otitis media due to Streptococcus pneumoniae: Immunopathogenic response in the chinchilla.

J Infect Dis d; Author: Robert W. Veltri, Philip M. Sprinkle. The chinchilla is the traditional animal model for most types of research related to the ear, specifically, hearing loss and otitis media. The chapter discusses all the different experimental models such as the models related to aural diseases, models related to hearing loss, and the models of aural pathologic conditions associated with hearing loss.

Middle ear infections (otitis media) in your chinchilla may happen during or after a respiratory infection. This is a common illness for chinchillas in general. If he has experienced something that put him into shock, he may also develop otitis media.

Your pet may also. Experimental otitis media in gerbils and chinchillas with Streptococcus pneumoniae, Haemophilus influenzae, and other aerobic and anaerobic bacteria. Infect. Immun. – Cited by: 7.Abstract. In considering the development of a vaccine to prevent otitis media, it is important to explore the rationale for such a vaccine, the epidemiology and spectrum of the disease, as well as its impact on child health, the etiology and pathogenesis of otitis media, especially as related to middle ear microbial pathogens, and the present status of otitis media vaccine by: Only 4% of chinchillas inoculated with influenza alone and 21% of chinchillas inoculated with S.

pneumoniae alone developed otitis media. Among the chinchillas that developed otitis media after inoculation with both pneumococcus and influenza, 73% of the affected ears contained effusion, and 27% of the affected ears showed tympanic membrane.